■ Education
2016, Ph.D. in Chemistry, Harvard University (Advisor: Eugene I. Shakhnovich)
2015, A.M. in History of Science, Harvard University (Advisor: Naomi Oreskes)
2011, B.S. in Chemistry and Physics, KAIST (Advisor: Yoon Sup Lee)
■ Employment
2020-, Assistant Professor, Department of Chemistry, Pusan National University
2019-2020, Research Assistant Professor, Natural Science Research Institute, KAIST
2016-2019, Postdoctoral Research Associate, Department of Biomedical Engineering, Washington University in St. Louis (Supervisor: Rohit V. Pappu)
■ Research Interests
Physical chemistry of living systems
Biological applications of statistical physics
Molecular modeling and design
■ Selected Publications (as of Sep 2020; * denotes co-first authors and † denotes (co-)corresponding authors)
1. S Han*, YN Kim*, G Jo, YE Kim, HM Kim, JM Choi,† Y Jung,† “Multivalent Interaction-Driven Assembly of Discrete, Flexible, and Asymmetric Supramolecular Protein Nano-Prisms,” Angewandte Chemie International Edition, in press
2. JM Choi, AS Holehouse, RV Pappu†, “Physical Principles Underlying the Complex Biology of Intracellular Phase Transitions,” Annual Review of Biophysics 49: 107-133 (2020)
3. JM Choi,* F Dar,* RV Pappu†, “LASSI: A Lattice Model for Simulating Phase Transitions of Multivalent Proteins,” PLOS Computational Biology 15 (10): e1007028 (2019)
4. JM Choi, RV Pappu†, “Improvements to the ABSINTH Forcefield for Proteins Based on Experimentally Derived Amino-Acid Specific Backbone Conformational Statistics,” Journal of Chemical Theory and Computation 15 (2): 1367-1382 (2019)
5. JM Choi, RV Pappu†, “Experimentally Derived and Computationally Optimized Backbone Conformational Statistics for Blocked Amino Acids,” Journal of Chemical Theory and Computation 15 (2): 1355-1366 (2018)
6. J Wang, JM Choi, AS Holehouse, HO Lee, X Zhang, M Jahnel, S Maharana, R Lemaitre, A Pozniakovsky, D Drechsel, I Poser, RV Pappu, S Alberti,† AA Hyman,† “A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins,” Cell 174 (3): 688-699 (2018)
7. JM Choi,† AI Gilson, EI Shakhnovich,† “Graph's Topology and Free Energy of a Spin Model on the Graph,” Physical Review Letters 118: 088302 (2017)
8. S Bershtein,* JM Choi,* S Bhattacharyya, B Budnik, E Shakhnovich,† “Systems-Level Response to Point Mutations in a Core Metabolic Enzyme Modulates Genotype-Phenotype Relationship,” Cell Reports 11 (4): 645-656 (2015)