RESEARCH INTERESTS
My research interests focus on the solution-state and solid-state NMR techniques to a variety of problems in biological chemistry. Some examples of research areas in which I am currently involved included:
1. secondary and tertiary structure of synthesized peptides in various conditions by NMR
2. activity modification through the hybridization of the antimicrobial peptides
3. water-soluble membrane protein design
4. interaction studies between the peptide and membrane by the solid-state NMR
SELECTED PUBLICATIONS
1. The interactions of ferric and ferrous cytochrome c with cardiolipin in phospholipid membranes studied by solid-state 2H and 31P NMR, Kim S., Shin K., Fujiwara T., Akutsu H., 1998, J. Mol. Struct . 441, p183
2. Osmotic stability of muramyl dipeptide-bearing liposomes and molecular miscibility in their membranes, Kim S., Kiyonaga H., Yamaguchi H., Morozumi T., Fujiwara T., Ando S., Tsuge H., Akutsu H., 1999, Bull. Chem. Soc. Japan , 72(3), p541
3. Identification of a substrate recognition site on Ubc9, Lin D., Tatham M.H., Yu B., Kim S., Hay R.T. Chen Y., 2002, J. Biol. Chem . 277(24) p21740
4. Role of an N-terminal site of Ubc9 in SUMO-1, -2, -3 binding and conjugation, Tahtam M.H., Kim S., Yu B., Jaffray E., Song J., Zheng J., Rodrigues M.S., Hay R.T., Chen Y., 2003, Biochemistry 42(33) p9959
5. Assignment of 1H, 13C and 15N resonances of the ARID domain of P270, Kim S., Zhu L., Yu B., Chen Y., 2003, J. Biomol. NMR 27(3) p277
6. The DNA-binding properties of the ARID-containing subunits of yeast and mammalian SWI/SNF complexes, Wilsker D., Patsialou A., Zumbrun S.D, Kim S., Chen Y., 2004, Nucleic Acids Research32(4) p1345
7. Structure and DNA-binding sites of the SWI1 AT-rich interaction domain (ARID) suggest determinants for sequence-specific DNA recognition, Kim S., Zhang Z., Upchurch S., Isern N., Chen Y., 2004, J. Biol. Chem . 279(16) p16670
8. Significant improvement of the pairwise contact energies for proteins, Heo M., Kim S., Moon E.J., Cheon M., Kim K., Chang I., 2004, J. Korean Phys. Soc. 44(6) p1571
9. Environment-Dependent One-Body Score Function for Proteins by Perceptron Learning and Protein Threading, Cheon M., Heo M., Moon E.J. Kim S., Chang I., Kim H., 2004, J. Korean Phys. Soc. 45(2) p550
10. Development of a Thermodynamic Approach to Clustering Ensemble Structures for a Native State of a Protein from NMR Experiment: Application to a Cancer Suppressor Protein P53, Kim S., Kim K., Heo M., Moon E.J., Cheon M., Chang I., Kim H., Lee W., 2004, J. Korean Phys. Soc . 45(2) p295
11. Role and Contribution of Ramachandran Angles in Protein Fold Recognition, Heo M., Kim S., Moon E.J., Cheon M., Kim K., Chang I., 2004, New Physics 48(3) p283
12. Significant improvement of the pairwise contact energies for proteins, Heo M., Kim S., Moon E.J., Cheon M., Kim K., Chang I., 2004, J. Korean Phys. Soc . 44(6) p1571
13. Identification of the Structural Change of Human Replication Protein A (hRPA) in the ssDNA Binding and Redox Potential, Suhkmann Kim, Andre Kim, Chun0Ri Li, Shin-Won Kang, Jang-Su Park, 2005, Bull. Kor. Chem. Soc . 26(8) p1168
14. Unique binding interactions among Ubc9, SUMO and RanBP2 reveal a mechanism for SUMO paralog selection, Michael H Tatham, Suhkmann Kim, Ellis Jaffray, Jing Song, Yuan Chen, Ronald T Hay, 2005, Nat. Struc. Mol. Biol . 12(1) p67
15. Perceptron learning of the pairwise-contact energies of proteins incorporating amino acids' environment, Muyoung Heo, Suhkmann Kim, Eun-Houng Moon, Mookyung Cheon, Kwanghoon Chung, Iksoo Chang, 2005, Physical Review E , 12 p11906
16. Phospholipid-Dependent Regulation of Cytochrome c3-Mediated Electron Transport Across Membranes, Suhkmann Kim, Toshinori Yamamoto, Yasuto Todokoro, Yuki Takayama, Toshimichi Fujiwara, Jang-Su Park, Hideo Akutsu, 2006, Biophys. J . 90 p506
17. Solid-state 2H NMR spectroscopy of retinal proteins in aligned membranes, Michael F. Brown, Maarten P. Heyn, Constantin Job, Suhkmann Kim, Stephan Moltke, Koji Nakanishi, Alexander A. Nevzorov, Andrey V. Struts, Gilma F. J. Salgado, Ingrid Wallat, 2007, Biochim. Biophys. Acta 1768 p2979
18. Interactions of membrane and PMAP-23 studies by 31P solid-state NMR spectroscopy, Siwon Kim, Suhkmann Kim, 2007 J. Kor. Mag. Res. Soc. 11(2) p110
PROFESSIONAL EXPERIENCES
Assistant Professor, Department of Chemistry, Pusan National University, Korea (2006-present)
P ROFESSIONAL SOCIETIES AND ACTIVITES
Korean Chemical Society
Korean Magnetic Resonance Society
Korean Society for Biochemistry and Molecular Biology